ABSTRACT
Objective To explore the clinical diagnostic value of CD64 index of neutrophil and serum amy-loid A(SAA)in early bacterial infections of children with respiratory tract.Methods A total of 152 children with respiratory tract infection admitted to Xianning Central Hospital from January 2017 to December 2017 were retrospectively analyzed.According to whether the pathogens were isolated,they were divided into 84 ca-ses of bacterial infection group and 68 cases of suspected respiratory tract infection group,at the same time,50 cases of healthy children in the same period were selected as the control group,the level of CD64 and SAA in three groups of patients was compared and analyzed,and the sensitivity,specificity,positive predictive value and negative predictive value of CD64 and SAA for the diagnosis of bacterial infection were also analyzed.Re-sults The CD64 index and SAA level in the bacterial infection group were higher than those of the suspected respiratory infection group(P< 0.05),after effective treatment,the two were significantly decreased(P<0.05).T he sensitivity,specificity,positive predictive value and negative predictive value of CD 64 index in diag-nosing bacterial infection were 92.9%,98.0%,98.7% and 89.1%,respectively,SAA was 96.4%,96.0%, 97.6% and 94.1%,respectively.Conclusion The detection of CD64 index and SAA level can help the early diagnosis,differential diagnosis and prognosis evaluation of respiratory tract bacterial infection in children, which is worthy of clinical promotion.